Meng, Fanping
Zhao, Jinfang
Tan, Anthony Tanoto
Hu, Wei
Wang, Si-Yu
Jin, Jiehua
Wu, Juan
Li, Yuanyuan
Shi, Lei
Fu, Jun-Liang
Yu, Shuangjie
Shen, Yingjuan
Liu, Limin
Luan, Junqing
Shi, Ming
Xie, Yunbo
Zhou, Chun-Bao
Wong, Regina Wanju
Lu-En, Wai
Koh, Sarene
Bertoletti, Antonio
Wang, Tingting
Zhang, Ji-Yuan
Wang, Fu-Sheng
Clinical trials referenced in this document:
Documents that mention this clinical trial
Immunotherapy of HBV-related advanced hepatocellular carcinoma with short-term HBV-specific TCR expressed T cells: results of dose escalation, phase I trial
https://doi.org/10.1007/s12072-021-10250-2
Funding for this research was provided by:
National Science and Technology Major Projects (2018ZX10301202)
Innovative Research Team in the National Natural Science Foundation of China (81721002)
Article History
Received: 30 April 2021
Accepted: 19 August 2021
First Online: 30 November 2021
Declarations
:
: Antonio Bertoletti is a co-founder of Lion TCR Pte. Ltd. a biotech company developing T cell receptors for treatment of virus-related cancers and chronic viral diseases. Anthony T. Tan is a scientific consultant for Lion TCR Pte. Ltd. Regina Wanju Wong, Wai Lu-En, Sarene Koh and Tingting Wang are employees of Lion TCR Pte. Ltd. Fanping Meng, Jinfang Zhao, Wei Hu, Si-Yu Wang, Jiehua Jin, Juan Wu, Yuanyuan Li, Lei Shi, Jun-Liang Fu, Shuangjie Yu, Yingjuan Shen, Limin Liu, Junqing Luan, Ming Shi, Yunbo Xie, Chun-Bao Zhou, Ji-Yuan Zhang, Fu-Sheng Wang have no conflicts of interest to disclose.
: This study was approved by the ethics committees of our hospital (2018096D) and fully complied with the Declaration of Helsinki and the Guideline for Good Clinical Practice, informed consent was obtained from eight subjects who participated in the study.
: Informed consent for publication was obtained from all authors.
: This article does not contain any studies with animals performed by any of the authors.
: Supporting data for this study are available from the corresponding author and the first author upon reasonable request. The measurements of HBsAg levels were repeated three times.