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Authors
Ohara, Masatsugu
Suda, Goki https://orcid.org/0000-0003-0098-9106
Kohya, Risako
Yasui, Yutaka
Tsuchiya, Kaoru
Kurosaki, Masayuki
Tani, Joji
Maekawa, Shinya
Enomoto, Nobuyuki
Chuma, Makoto
Morimoto, Manabu
Kaneko, Shun
Nakagawa, Mina
Asahina, Yasuhiro
Komori, Atsumasa
Kugiyama, Yuki
Baba, Masaru
Nakamura, Akihisa
Ito, Jun
Yamada, Ren
Hosoda, Shunichi
Yamamoto, Yoshiya
Yoshida, Sonoe
Sho, Takuya
Sasaki, Takashi
Yoda, Tomoka
Meno, Akimitsu
Yasuura, Naohiro
Fu, Qingjie
Yang, Zijian
Maehara, Osamu
Ohnishi, Shunsuke
Tokuchi, Yoshimasa
Kitagataya, Takashi
Kawagishi, Naoki
Nakai, Masato
Ogawa, Koji
Sakamoto, Naoya
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Funding
Funding for this research was provided by:
the Japan Agency for Medical Research and Development (grant numbers JP25fk0210126, JP25fk0310545, JP24fk0210121, JP25fk0210142, JP25fk0310551, JP25fk0210123, JP25fk0310535, JP25fk0210157, JP25fk0310543, JP25fk0210172 JP25fk0210174, JP25fk0210143)
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Article History
Received: 30 April 2025
Accepted: 2 July 2025
First Online: 28 August 2025
Declarations
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: Prof. Naoya Sakamoto received lecture fees from Chugai Pharmaceutical Co., Ltd., and research grants from Gilead Sciences, Inc., and AbbVie, Inc. Dr. Goki Suda received research grants from Gilead Sciences. Prof. Atsumasa Komori received a research grant from Chugai Pharmaceutical Co., Ltd. Prof. Masayuki Kurosaki received honoraria for lecture from Eisai Co., Ltd., Chugai Pharmaceutical Co., Ltd., AstraZeneca, Gilead Sciences, and AbbVie, Inc. Dr. Kaoru Tsuchiya received honoraria for lecture from Eisai Co., Ltd., Chugai Pharmaceutical Co., Ltd., AstraZeneca, and Takeda Pharmaceuticals. Dr. Yutaka Yasui received honoraria for lecture from Eisai Co., Ltd., Chugai Pharmaceutical Co., Ltd., AstraZeneca, and Eli Lilly Japan K.K. All remaining authors have declared no conflicts of interest.
: The study protocol followed the ethical guidelines of the Declaration of Helsinki, and all participating patients provided informed consent. This study was approved by the ethics committee of Hokkaido University Hospital (020–0267) and the committee of each participating institution.
