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Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines

Crossref DOI link: https://doi.org/10.1007/s12079-018-0456-4

Published Online: 2018-02-04

Published Print: 2018-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

van Wenum, Martien

Adam, Aziza A. A.

van der Mark, Vincent A.

Chang, Jung-Chin

Wildenberg, Manon E.

Hendriks, Erik J.

Jongejan, Aldo

Moerland, Perry D.

van Gulik, Thomas M.

Oude Elferink, Ronald P.

Chamuleau, Robert A. F. M.

Hoekstra, Ruurdtje http://orcid.org/0000-0002-7325-2394
Funding

Funding for this research was provided by:

ZonMw (114021009)

EU (n304914)
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Article History

Received: 30 November 2017

Accepted: 25 January 2018

First Online: 4 February 2018

Compliance with ethical standards

:

: RC and RH are inventors of the patent-protected HepaRG-based AMC-Bioartificial liver that is currently being commercialized through the university spin-off company Hep-Art Medical Devices B.V of which RC is unsalaried Chief Scientific Officer. RH was previously employed part-time by Hep-Art Medical Devices B.V.The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.