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Article History

Received: 22 October 2018

Accepted: 29 October 2018

First Online: 17 November 2018

Compliance with ethical standards

:

: MM reports personal fees from AstraZeneca, Roche, Lilly, Bristol-Myers Squibb, Pfizer, Boehringer Ingelheim, Novartis, Tesaro, outside the submitted work. OJ reports grants from Astra Zeneca and personal fees from Astra Zeneca, BMS, MSD, ROCHE, Boehringer Ingelheim, Lilly outside the submitted work. MP reports grants from BMS, Roche and personal fees from BMS, MSD, ROCHE, Pierre Fabre, Novartis; Takeda, Lilly, Pfizer outside the submitted work. NR reports advisory Board/Consultancy/Speaker honoraria from MSD, Bristol-Myers, Roche, Boehringer Ingelheim, Guardant Health, Pfizer, Abbie, Ipsen, Novartis, Astra-Zeneca, Lilly, Takeda outside the submitted work; Research Funding from Pfizer, NanoString Technology, and Institutional financial interests related to clinical trials and patient recruitment. GC reports non-financial support from Millennium Pharmaceuticals, Inc., during the conduct of the study; personal fees from ARIAD, AstraZeneca, Roche, Pfizer, BMS, Boehringer Ingelheim, MSD outside the submitted work. YG reports personal fees from Roche, Boehriger-ingelheim, Lilly, MSD, Pfizer, BMS outside the submitted work. JMT reports personal fees from Roche, Boehriger-ingelheim, BMS, Astra Zeneca, MerckSerono outside the submitted work. AI, EC, MG, have not reported any potential conflicts of interest.

: The current study has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

: No informed consent was necessary for this guideline.