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Article History

Received: 1 April 2020

Accepted: 10 May 2020

First Online: 23 May 2020

Compliance with ethical standards

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: E.L. reports receiving grants from Fondazione AIRC (Associazione Italiana per la Ricerca sul Cancro) and from the Italian Ministry of Health, and faculty remuneration from ESMIT (European School of Multimodality Imaging & Therapy) and MI&T congress. A. Chiti received speaker honoraria from General Electric and Sirtex Medical System, acted as scientific advisor to Blue Earth Diagnostics and Advanced Accelerator Applications, and benefited from an unconditional grant from Sanofi to Humanitas University. All honoraria are outside the scope of the submitted work.

: All legal requirements were met in accomplishing this study (including ethical and radiation protection regulations). All procedures performed in the protocol ICH/382/216 protocol involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

: All patients have signed the informed consent prior to any investigation.