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Article History

Received: 6 March 2024

Accepted: 26 April 2024

First Online: 11 June 2024

Declarations

:

: All authors have completed the ICMJE uniform disclosure form at declare: EC has served as an advisor or consultant for AstraZeneca, Boehringer Ingelheim, BMS, MSD, Novartis, Roche, and Takeda; he has served as a speaker for AstraZeneca, Boehringer Ingelheim, BMS, MSD, Novartis, Pfizer, Roche, and Takeda; he has received grant support from MSD and has received honoraria from BMS, Pfizer, Roche, and Takeda. DR-A has served as an advisor for MSD, Regeneron, BMS, GSK & Lilly has received honoraria for lectures from MSD, Roche, BMS, Novartis, Takeda, Lilly, and AstraZeneca; he has received support for attending meetings and/or travel from Roche, MSD, Novartis and Sanofi. RL has received consulting fees from Roche, AstraZeneca, Boehringer Ingelheim, Novartis, and BMS; He has received payment or honoraria for lectures from Kyowa Kirin, Pierre-Fabre, Takeda, AstraZeneca, BMS, Novartis, Roche, and Pfizer; he has received support for attending meetings and/or travel from MSD. BM has served as an advisor for Roche, BMS, MSD, Boehringer Ingelheim, Takeda, and Abbvie; he has received support for attending meetings and/or travel from Roche, Pfizer, Merck Serono, Boehringer-Ingelheim, and AstraZeneca. GS has received honoraria from Sanofi and has received support for attending meetings and/or travel from Gilead and MSD. MAS has received honoraria from Takeda and Roche and has received support for attending meetings and/or travel from Roche and PharmaMar. PC has received honoraria from Roche, Janssen, Pfizer, Takeda, and BMS and has received support for attending meetings and/or travel from Roche, Janssen, Pfizer, Takeda, and BMS. RB has served as an advisor for AstraZeneca, Roche, Amgen, and MSD; he has received honoraria from BMS, Roche, AstraZeneca, Lilly, MSD, and Pfizer; he has received support for attending meetings and/or travel from AstraZeneca and Roche. JLGL has served as an advisor for MSD, Janssen-Cilag, BMS, Boehringer Ingelheim, and Amgen; he has received payment as an expert testimony from MSD, Janssen-Cilag, BMS, Boehringer Ingelheim, and Amgen; he has received honoraria from MSD, AstraZeneca, Roche, Pfizer, Janssen-Cilag, Novartis, Astellas, and BMS; he has received support for attending meetings and/or travel from MSD, Takeda, BMS, Roche, Pfizer, and Janssen-Cilag. JBB has received grants from Pfizer and Roche; he has received honoraria from AstraZeneca, Pfizer, MSD, BMS, Roche, and Sanofi; he has received support for attending meetings and/or travel from MSD, Takeda, and Roche. AP has served as an advisor for AstraZeneca; he has received payment as an expert testimony from AstraZeneca, Takeda, Roche, BMS, MSD, and Merck; he has received honoraria from AstraZeneca, Takeda, Roche, BMS, MSD, and Merck; he has received support for attending meetings and/or travel from Takeda, AstraZeneca & Merck. MP has been awarded research grants from AstraZeneca, Roche, BMS, Boehringer-Ingelheim, and Takeda; he has served as a consultant for AstraZeneca, BMS, Boehringer-Ingelheim, Celgene, MSD, Roche, Takeda, and Thermo-Fisher. All other authors declare no conflicts of interest.

: Not required as this study only used anonymised and aggregated data.

: Not applicable.

: The study was approved by Clinical Research Ethical Comitte from Puerta de Hierro Hospital, and patients alive in the moment their inclusion signed a informed consent.