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Article History

Received: 22 October 2025

Accepted: 13 December 2025

First Online: 23 January 2026

Declarations

:

: Rosario Vidal-Tocino declares that she has received fees for giving presentations, consulting, and/or attending courses or conferences from Amgen, Merck, Servier, Bristol Myers Squibb, MSD, GSK, Roche, Pierre-Fabre, Astellas, and Lilly. María Hernández Miguel declares that she has received fees for giving presentations or talks from Astellas. Lourdes Martinez-Berganza Asensio declares that she has received fees for giving presentations and attending courses from Astra Zeneca, Boehringer Ingelheim, Sysmex, Astellas, and GSK. Ruth Vera García declares that she has received fees for giving presentations and consulting for Roche, Amgen, Takeda, MSD, and Servier. Elena M. Brozos Vázquez declares that she has received fees for giving talks, attending conferences, and consulting. Cruz Bartolomé-Moreno, Rafael Manuel Micó Pérez, Raúl Hernanz, Yolanda Ginés, Fátima Santolaya Sardinero, and Jacinto Batíz Cantera declare that they have no conflicts of interest.

: This research presents an accurate account of the work performed, all data presented are accurate and methodologies detailed enough to permit others to replicate the work. This manuscript represents entirely original works and or if work and/or words of others have been used, that this has been appropriately cited or quoted and permission has been obtained where necessary. This material has not been published in whole or in part elsewhere. The manuscript is not currently being considered for publication in another journal. No generative AI or AI-assisted technologies were used in the writing or image creation process. All authors have been personally and actively involved in substantive work leading to the manuscript and will hold themselves jointly and individually responsible for its content.

: For this type of study formal consent is not required.