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Authors
Saika, Wataru
Yamazaki, Hiromi
Tanaka, Shota
Lin, Min
Oshima, Seigi
Gao, Ziyu
Nomura, Masaki
Zang, Weijia
Koike, Yui
Xiao, Muran
Ito, Hiromi
Matsumoto, Naomi
Yamasaki, Takaya
Nishimura, Koutarou
Murata, Makoto
Inoue, Daichi https://orcid.org/0000-0002-7947-6540
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Funding
Funding for this research was provided by:
Japan Society for the Promotion of Science (JP21K08432)
Japan Society for the Promotion of Science (JP24K22138)
Japan Society for the Promotion of Science (JP23K07824)
Japan Society for the Promotion of Science (JP24H00866)
Japan Society for the Promotion of Science (JP20H00537)
Japan Society for the Promotion of Science (JP23H00430)
Japan Society for the Promotion of Science (16H06279)
Japan Society for the Promotion of Science (JP24K21298)
Japan Science and Technology Agency CREST (JPMJCR23B7)
Japan Agency for Medical Research and Development (JP23ama221126)
Japan Agency for Medical Research and Development (JP24ama221135)
Naito Foundation
American Society of Hematology
Japanese Society of Hematology
Ono Medical Research Foundation
Ono Pharmaceutical
Mitsubishi Foundation
The Cell Science Research Foundation
Kobayashi Foundation for Cancer Research
Takeda Science Foundation
Chugai Foundation for Innovative Drug Discovery Science
Foundation for Promotion of Cancer Research
Friends of Leukemia Research Fund
Princess Takamatsu Cancer Research Fund
Mochida Memorial Foundation for Medical and Pharmaceutical Research
MSD Life Science Foundation, Public Interest Incorporated Foundation
SENSHIN Medical Research Foundation
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Article History
Received: 18 August 2025
Revised: 5 November 2025
Accepted: 5 November 2025
First Online: 11 November 2025
Declarations
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: Abbvie, Sumitomo Dainippon Pharma and Mitsubishi Tanabe Pharma (D.I.), JCR Pharmaceuticals, Chugai Pharmaceutical, Otsuka Pharmaceutical, Mochida Pharmaceutical and Nippon Kayaku (M.M.). The remaining authors declare no competing interests.
: Not applicable.
: All animal procedures were approved by the Animal Experiments Committee of the Graduate School of medicine at The University of Osaka (24-055-006) and the Institutional Animal Care and Use Committees of FBRI (22-10).
