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Article History

Received: 22 July 2025

Revised: 3 December 2025

Accepted: 8 December 2025

First Online: 24 December 2025

Declarations

:

: Hiroki Yamaguchi received consulting fees from Nippon Shinyaku, AbbVie, PharmaEssentia, Sumitomo Pharma, Novartis Pharma, Daiichi-Sankyo; payment/honoraria from Nippon Shinyaku, Sanofi, PharmaEssentia, Janssen Pharmaceutical, Novartis Pharma, Kyowa Kirin, Daiichi-Sankyo, Alexion Pharma, AbbVie, AstraZeneca, Astellas Pharma, Shionogi Pharma, Chugai Pharmaceutical, Ono Pharmaceutical, Genmab; medical writing support from PharmaEssentia Japan. Yuka Sugimoto is editor of International Journal of Hematology and received research funding from PharmaEssentia, Toyo Kohan, Incyte Biosciences Japan, MSD, Sumitomo Pharma, Sobi Japan; payment/honoraria from Novartis Pharma, PharmaEssentia Japan, GlaxoSmithKline; medical writing support from PharmaEssentia Japan. Akihiko Gotoh received research funding from Asahi Kasei, Taiho Pharmaceutical, Otsuka Pharmaceutical, Kyowa Kirin, Chugai Pharmaceutical; consulting fees from PharmaEssentia Japan, Chugai Pharmaceutical, Alexion Pharma; honoraria from Novartis Pharma, Alexion Pharma, Asahi Kasei, Ono Pharmaceutical, Taiho Pharmaceutical, Takeda Pharmaceutical, Nippon Shinyaku, Chugai Pharmaceutical, Otsuka Pharmaceutical, Sumitomo Dainippon Pharma, Daiichi-Sankyo, GlaxoSmithKline, Kyowa Kirin, Janssen Pharmaceutical, Pfizer Japan, Sanofi; data safety monitoring board/advisory board fees from PharmaEssentia Japan, Chugai Pharmaceutical, Alexion Pharma; medical writing support from PharmaEssentia Japan. Shuichi Ota received payment/honoraria from Novartis Pharma, Bristol Myers Squibb, Takeda Pharmaceutical, Janssen Pharmaceutical, AstraZeneca, Amgen, AbbVie, Sanofi, PharmaEssentia; medical writing support from PharmaEssentia Japan. Norio Komatsu is a board member of PharmaEssentia Japan; received medical writing support from PharmaEssentia Japan. Keita Kirito received payment/honoraria from PharmaEssentia Japan, GlaxoSmithKline, Novartis Pharma; medical writing support from PharmaEssentia Japan. Hiromi Igari is an employee of PharmaEssentia Japan. Tatsunori Murata and Keigo Hanada are employees of CRECON Medical Assessment Inc.