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Nano-cocrystal Delivery System of Curcumin: Physicochemical Characterization, Antioxidant Activity, Cytotoxicity Against MCF-7 Cells and Topical Gel Formulation

Crossref DOI link: https://doi.org/10.1007/s12247-026-10379-3

Published Online: 2026-02-21

Published Print: 2026-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

saleem, Amna

Afzal, Hafsa

ul Hassan jawa, Najam

Kamran, Sairah Hafeez

Ijaz, Qazi Amir

Abbas, Nasir

Latif, Sumera
Funding

Funding for this research was provided by:

Higher Education Commision, Pakistan (Ref No. 20-14768/NRPU/R&D/HEC/2021 2021)
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Text and Data Mining valid from 2026-02-21

Version of Record valid from 2026-02-21
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Article History

Received: 28 September 2025

Accepted: 5 January 2026

First Online: 21 February 2026

Declarations

:

: Not applicable.

: A preliminary version of this work was previously disseminated as a preprint by Amna Saleem, Hafsa Afzal, Najam ul Hassan Jawa, Misbah Hameed, Mobina Manzoor, Qazi Amir Ijaz, Nasir Abbas and Sumera Latif entitled “Integration of cocrystal and nanocrystal techniques to ameliorate solubility, topical antioxidant activity and cytotoxicity of curcumin” on the Research Square preprint server. The preprint was posted on 14 May, 2025 and is available at . This version is identified as “This is a Preprint; it has not been peer reviewed by a journal”. The present manuscript represents the peer-review submission of the same study with refinements made following the preprint posting.

: Authors declare that no AI or AI assisted tools have been used in the preparation of the text and take full responsibility for the content of the published article.

: The authors declare no competing interests.

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