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Structure-Guided Discovery of Phytochemical Leads Targeting the Glucocorticoid Receptor (NR3C1) for Anti-Stress Activity: Computational Insights from Multi-Tier Virtual Screening and Structural Dynamics

Crossref DOI link: https://doi.org/10.1007/s12247-026-10512-2

Published Online: 2026-03-04

Published Print: 2026-06

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Karuppiah, Shanthini

Jayaraman, Manikandan

Muthuvairam Subbulakshmi, Maharaja

Jeyaraman, Jeyakanthan

Narayanaswamy, Komalavalli
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Text and Data Mining valid from 2026-03-04

Version of Record valid from 2026-03-04
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Article History

Received: 17 November 2025

Accepted: 16 February 2026

First Online: 4 March 2026

Declarations

:

: Not applicable.

: This study did not involve human participations, animal models, or clinical data requiring ethical approval. All the computational analysis were conducted using the publicly available datasets and tools.

: The authors declare no competing financial interest.

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