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Modulation of Glutamate Release by Dexmedetomidine Preserves Dendritic Spines and Alleviates Cognitive Impairment in a Murine Model of Perioperative Neurocognitive Disorder

Crossref DOI link: https://doi.org/10.1007/s12264-025-01518-w

Published Online: 2025-10-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Yan

Li, Junzhao

Wang, Xueju

Zhang, Zhongyu

Long, Shuai

Li, Chuanyu Edward

Liu, Yan

Chu, John Man Tak

Chang, Raymond Chuen-Chung

Wong, Gordon Tin-Chun https://orcid.org/0000-0002-8127-4593
Zhang, Yong https://orcid.org/0000-0001-8765-7037
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Text and Data Mining valid from 2025-10-17

Version of Record valid from 2025-10-17
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Article History

Received: 24 January 2025

Accepted: 27 May 2025

First Online: 17 October 2025

Conflict of interest

: The authors declare no conflict of interest.

: All animal experiments were approved and conducted in accordance with IACUC regulations at Peking University Health Science Center or the Department of Health.

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