Akinrinade, Oyediran
Lesurf, Robert
Ambrose, J. C.
Arumugam, P.
Bleda, M.
Boardman-Pretty, F.
Boustred, C. R.
Brittain, H.
Caulfield, M. J.
Chan, G. C.
Fowler, T.
Giess, A.
Hamblin, A.
Henderson, S.
Hubbard, T. J. P.
Jackson, R.
Jones, L. J.
Kasperaviciute, D.
Kayikci, M.
Kousathanas, A.
Lahnstein, L.
Leigh, S. E. A.
Leong, I. U. S.
Lopez, F. J.
Maleady-Crowe, F.
Moutsianas, L.
Mueller, M.
Murugaesu, N.
Need, A. C.
O‘Donovan, P.
Odhams, C. A.
Patch, C.
Perez-Gil, D.
Pereira, M. B.
Pullinger, J.
Rahim, T.
Rendon, A.
Rogers, T.
Savage, K.
Sawant, K.
Scott, R. H.
Siddiq, A.
Sieghart, A.
Smith, S. C.
Sosinsky, A.
Stuckey, A.
Tanguy, M.
Thomas, E. R. A.
Thompson, S. R.
Tucci, A.
Walsh, E.
Welland, M. J.
Williams, E.
Witkowska, K.
Wood, S. M.
Lougheed, Jane
Mondal, Tapas
Smythe, John
Altamirano-Diaz, Luis
Oechslin, Erwin
Mital, Seema http://orcid.org/0000-0002-7643-4484
,
Funding for this research was provided by:
Canadian Institutes of Health Research (PJT 175034)
Heart and Stroke Foundation of Canada
National Institute for Health and Care Research
Wellcome Trust
Article History
Received: 12 March 2023
Accepted: 4 July 2023
First Online: 21 July 2023
Declarations
:
: SM is on the Advisory Board of Bristol Myers Squibb, and Tenaya Therapeutics. The remaining authors have nothing to disclose.
: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki declaration of 1975, as revised in 2000 (5). Informed consent was obtained from all patients for being included in the study.
: No animal studies were carried out by the authors for this article.
: Sequencing data from the Ontario Registry are deposited in the European Genome-Phenome Archive (EGA) under accession EGAS00001004929, and are available for download upon approval by the Data Access Committee. The 100,000 Genomes Project data are available to researchers and trainees using the Genomics England Research Environment upon institutional approval through their Participation Agreement process. Additional data generated or analyzed during this study are included in the supplementary information files, and additional raw data used for figures and results are available from the corresponding author on reasonable request.
: All authors contributed to the study conception and design, and to data collection. Data analysis was performed by [Oyediran Akinrinade] [Robert Lesurf]. The first draft of the manuscript was written by [Oyediran Akinrinade]. Funding was acquired by [Seema Mital]. All authors commented on manuscript versions and read and approved the final manuscript.