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Article History

Received: 22 January 2025

Accepted: 12 March 2025

First Online: 25 March 2025

Declarations

:

: The present study was approved by the Danish Animal Experiments Inspectorate (2015–15-0201–00570) and conducted in accordance with the ethical and welfare regulations of Aarhus University, national guidelines with European legislation (Directive 2010/63/EU). The study is reported as per the ARRIVE guidelines.

: Clinical trial registration number: Not applicable.The present study was approved by the Danish Animal Experiments Inspectorate (2015–15-0201–00570). All institutional and national guidelines for the care and use of laboratory animals were followed and approved by the appropriate institutional committees. No human studies were carried out by the authors for this article.

: No human studies were carried out by the authors for this article. All institutional and national guidelines for the care and use of laboratory animals were followed and approved by the appropriate institutional committees.

: EHC has received institutional research grants from Abbott and Biotronik and speaker fees from Abbott. NRH received institutional research grants and speaker fees from Abbott.All other authors have no conflicts of interests to declare.