Zhang, Yin
Yang, Wenlong
Zhang, Jinyan
A, Jixiang
Shen, Jinye
Qi, Zhiyong
Qian, Juying
Sun, Aijun
Ge, Junbo
Zhang, Shuning https://orcid.org/0000-0001-7800-8828
Funding for this research was provided by:
the National Natural Science Foundation of China (82200297)
the National Natural Science Foundation of China (82100355)
Shanghai Sailing Program (21YF1433200)
Shanghai Sailing Program (21YF1406000)
Natural Science Foundation of Shanghai (21ZR1413500)
Shanghai Top Priority center construction project (2022ZZ01010)
Shanghai Clinical Research Center for Interventional Medicine (19MC1910300)
Article History
Received: 14 September 2025
Accepted: 27 February 2026
First Online: 24 March 2026
Declarations
:
: All institutional and national guidelines for the care and use of laboratory animals were followed and approved by the Zhongshan Hospital Animal Ethics Committee (Protocol No. 2020–045).
: This study confirms that PAGln is one of the critical factors influencing angiogenesis, and the administration of β-blockers can significantly mitigate the adverse effects associated with PAGln.
: Not applicable (No human studies were carried out by the authors for this article).
: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.