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Article History

Received: 17 October 2019

Accepted: 16 March 2020

First Online: 20 March 2020

Compliance with ethical standards

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: The authors declare that they have no conflict of interest.

: All authors listed above have reviewed and verified the manuscript for accuracy. All authors have consented to be an author and publish the manuscript.

: Present study was performed using publicly-available datasets retrieved from GEO database. As regards GSE70947, the original study was approved by REC SouthEast (Regional Ethical Committee for Medical and Health Research Ethics) and by the Ethical Committee for Aarhus county and by “Datatilsynet” (The Data Inspectorate, an independent administrative body under the Ministry of Government Administration and Reform), whereas as regards GSE33526, the original study was approved by the Institutional Review Boards at Baystate Medical Center and University of Massachusetts Amherst. In both cases, all patients consented to provide excess tissues not needed for research purposes.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.