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Authors
Alsumali, Adnan https://orcid.org/0000-0002-5139-3583
McLaughlin, Vallerie
Chevure, Jestinah
Klok, Rogier https://orcid.org/0000-0001-6584-4886
Zhang, Wenjie https://orcid.org/0000-0001-8301-2821
Martinez, Eliana C.
Pausch, Christine https://orcid.org/0000-0002-1866-9015
De Oliveira Pena, Janethe
van de Wetering, Gijs
Jootun, Murvin
Lautsch, Dominik https://orcid.org/0000-0003-3803-1817
Hoeper, Marius M. https://orcid.org/0000-0001-9086-2293
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Clinical Trials BETA
Clinical trials referenced in this document:
nct04576988 at ClinicalTrials.govDocuments that mention this clinical trial
Population Health Model Predicting the Long-Term Impact of Sotatercept on Morbidity and Mortality in Patients with Pulmonary Arterial Hypertension (PAH)
https://doi.org/10.1007/s12325-023-02684-x
Advances in the management of pulmonary arterial hypertension
https://doi.org/10.1136/jim-2021-002027
Long-Term Mortality and Morbidity Impact on Patients with Pulmonary Arterial Hypertension (PAH) If Access to Sotatercept Is Delayed: A Simulation Model
https://doi.org/10.1007/s12325-025-03241-4
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Funding
Funding for this research was provided by:
Merck & Co., Inc., Rahway, NJ, USA
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Article History
Received: 14 March 2025
Accepted: 9 May 2025
First Online: 17 June 2025
Declarations
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: Wenjie Zhang and Gijs van de Wetering are employees of OPEN Health, which received funding from Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, to conduct the study. Adnan Alsumali, Janethe de Oliveira Pena, Rogier Klok, Dominik Lautsch, Jestinah Chevure, Murvin Jootun and Eliana Martinez are employees or were employees of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, at the time the study was done and may hold stock in Merck & Co., Inc., Rahway, NJ, USA. Vallerie McLaughlin is a consultant for Aerovate, Altavant Sciences, Bayer, CVS Caremark, CorVista Health, Gossamer Bio, Janssen, Merck, and United Therapeutics; has received grants from Aerovate, Altavant Sciences, Merck, Gossamer Bio, Janssen, and SoniVie; and received stock from Clene. Christine Pausch has nothing to disclose. Marius M. Hoeper is a consultant and speaker for Acceleron Pharma, Inc., Actelion, AOP Orphan Pharmaceuticals, Bayer, Ferrer, GlaxoSmithKline, Janssen, and MSD.
: This study relied on previously conducted studies and did not involve any new studies requiring the direct participation of human subjects; thus, ethics board approval was not required. The authors sought and received permission from the registry owners to access and use data from the COMPERA PAH registry.
