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Unprecedented case of rapid-onset autoimmune hepatitis triggered by COVID-19 mRNA vaccination, complicated by concurrent severe hemophagocytic lymphohistiocytosis and acute liver failure in a previously healthy adult: a multidisciplinary approach and review of therapeutic interventions

Crossref DOI link: https://doi.org/10.1007/s12328-025-02109-y

Published Online: 2025-04-08

Published Print: 2025-06

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Khalil, Zeyad https://orcid.org/0009-0007-4692-1998
Fouly, Mohamed

Helito, Paulo
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Text and Data Mining valid from 2025-04-08

Version of Record valid from 2025-04-08
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Article History

Received: 27 September 2024

Accepted: 22 February 2025

First Online: 8 April 2025

Declarations

:

: The authors have no relevant financial or non-financial interests to disclose.

: The consent process was conducted by ethical guidelines established by the [Institution’s Ethics Committee of October 6th University], ensuring the patient’s autonomy, confidentiality, and rights were fully protected.

: Written informed consent was obtained from the patient for the publication of this case report and the accompanying images. The patient has been informed that the information and images will be anonymized, ensuring that no identifying details will be disclosed. This consent process was conducted by ethical guidelines established by the [Institution’s Ethics Committee of October 6th University], ensuring the patient’s autonomy, confidentiality, and rights were fully protected.

: Informed consent was obtained from the patient to participate in the study.

: Informed consent was obtained from the patient for publication agreement of the paper.

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