Document is current

Article History

Received: 26 January 2025

Revised: 8 July 2025

Accepted: 9 July 2025

First Online: 13 August 2025

Declarations

:

: The Working Group members and the Evidence-to-Decision (EtD) experts of the RTX Guidelines have all signed the Conflict-of-Interest Declaration. The Working Group consists of nephrologists from the Children’s Hospital of Fudan University and Children’s Hospital of Nanjing Medical University, who voluntarily participated in working group meetings, literature retrieval & screening, evidence extraction, bias risk assessment, and systematic review/meta-analysis, all for free. The Methodology Team is from Fudan University GRADE Center and volunteers to provide support and training for the methodologies used in the guideline preparation. The EtD meetings were offline, and funded by the research project titled “The Efficacy and Safety of Rituximab in Reducing Relapse of Steroid-sensitive Nephrotic Syndrome in Children: A Single-Arm, Open-Label, Multicenter Clinical Study”. The review of the manuscripts was by unpaid experts through correspondence. Author Hong Xu, Jian-Hua Mao, and Ai-Hua Zhang are members of the Editorial Board for World Journal of Pediatrics. They were not involved in the peer-review process or the decision to accept this manuscript for publication. The paper was handled by other Editors and has undergone rigorous peer-review process.

: Not required.

: No patients participated in this study. However, parents of pediatric nephrotic syndrome patients and social workers, who were adequately informed and equipped with necessary decision support, actively engaged in the Evidence-to-Decision (EtD) meeting for the formulation of recommendations.