Document is current

Article History

Received: 22 March 2023

Accepted: 11 July 2023

First Online: 22 July 2023

Declarations

:

: All applicable international, national, and/or institutional guidelines for the care and use of animals were followed according to bio-ethical procedures accepted by the American Association for Laboratory Animal Sciences (IACUC).All animal studies have been approved by the appropriate ethics committee and have therefore been performed in agreement with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. Guidelines for ethics approval according to specific national laws were revised by the Honorary Committee of Animal Experimentation (CHEA), from Uruguay. Animal ethics and experimentation protocols were examined to pursue the international guidelines on animal experimentation mentioned above (approval protocol number 071140-000467-09, CHEA). No anesthesia was used to avoid interferences with the heart function. To euthanize the animals, instantaneous occipital concussion was used.

: All authors have declared their consent to participate.

: All the authors have declared their consent to publish.

: The authors declare no competing interests.