Lespay-Rebolledo, C.
Tapia-Bustos, A.
Bustamante, D.
Morales, P.
Herrera-Marschitz, M.
Funding for this research was provided by:
FONDECYT Chile (1190562; 1180042; 1120079)
CONICYT Operational Support, Chile (21140281, 21151232)
Article History
Received: 14 March 2019
Revised: 8 May 2019
Accepted: 9 May 2019
First Online: 11 June 2019
Compliance with ethical standards
:
: All procedures were conducted in accordance with the animal care and use protocol established by a Local Ethics Committee for experimentation with laboratory animals at the Medical Faculty, University of Chile (Protocol CBA no. 0722 FMUCH) and by an ad hoc commission of the Chilean Council for Science and Technology Research (CONICYT), endorsing the principles of laboratory animal care (NIH; No. 86-23; revised 1985). Animals were permanently monitored (on 24 h basis) regarding well being, following the ARRIVE guidelines for reporting animal studies (www.nc3rs.org.uk/ARRIVE).