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CD206 accelerates hepatocellular carcinoma progression by regulating the tumour immune microenvironment and increasing M2-type polarisation of tumour-associated macrophages and inflammation factor expression

Crossref DOI link: https://doi.org/10.1007/s12672-024-01309-1

Published Online: 2024-09-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Mao, Zhiyuan

Han, Yalin

Li, Yinglin

Bai, Li
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Text and Data Mining valid from 2024-09-13

Version of Record valid from 2024-09-13
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Article History

Received: 20 December 2023

Accepted: 3 September 2024

First Online: 13 September 2024

Declarations

:

: This study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of the First Medical Center, Chinese PLA General Hospital.

: According to the criteria set by the Hospital Ethics Committee based on the Guidelines for Humane Endpoint Review of Animal Experiments in China, the tumor length on the back of mice should be less than 17 mm.In this study, the size of the tumour was measured with Vernier callipers, and the length (L) and width (W) of the tumour were recorded. The volume (V) was calculated as: (L × W<sup>2</sup>) × 0.5. In this study, all tumors did not exceed 15 mm in length and 1 cm<sup>3</sup> in volume, which meets the requirement for maximal tumor burden.

: Not applicable.

: The authors declare no competing interests.

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