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Article History

Received: 26 July 2024

Accepted: 11 November 2024

First Online: 25 November 2024

Declarations

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: The materials directly related to human body are the clinical specimens of HCC or the paired non-tumor tissues. Written informed consent and authorisation was obtained from the patient for the collection, containing and usage of the clinical specomens. The use of these clinical specimens was approved by the Ethics Committee of the 920th Hospital of the PLA Joint Logistic Support Force, Kunming City 650032, Yunnan Province, P.R. China. The usages, and the experiments related these clinical specimens were performed in the 920th Hospital of the PLA Joint Logistic Support Force, Kunming City 650032, Yunnan Province, P.R. China in accordance with the Declaration of Helsinki (World Health Organization). For the animal ethic declaration, the nude mouse model was used as experimental animals in the presence work. The animal experiments were performed in the First medical center of Chinese PLA General Hospital, Beijing 100853, P.R. China. The experimental design, methods and the protocol of animal experiments were reviewed and approved by the Institutional Animal Care and Usage Committee (IACUC) of the First Medical Center of General Hospital of Chinese PLA. All the animal experiments were performed in accordance with the U.K. Animals Act, 1986 (Scientific Procedures) guidelines.

: The authors declare no competing interests.