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Authors
Huang, Xunhua
Chen, Yongzhong
Chen, Jiayuan
Lin, Jinkun
Zhuang, Yixue
Huang, Meixia
Yu, Hongmin
Wang, Mingfei
Wang, Yingzheng
Wang, Yinghao
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Funding
Funding for this research was provided by:
Ministry of Science and Technology of Fujian Province
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Article History
Received: 19 June 2025
Accepted: 17 October 2025
First Online: 7 November 2025
Declarations
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: This research was approved by the Committee on the Ethics of Animal Experiments of Fujian University of Traditional Chinese Medcine (Animal Protocol NO.FJTCM IACUC 2022063). The animal experiments in this study were conducted in accordance with the Basel Declaration. The maximal permitted tumor burden was defined as a volume ≤ 1,500 mm³ (or 15 mm diameter), consistent with institutional guidelines for humane endpoints. Throughout the study, no tumor exceeded this limit. Mice were monitored every 48 h; all were euthanized upon reaching ≤ 1,500 mm³ or if distress signs (e.g., weight loss > 20%, lethargy) occurred. No exceptions occurred.
: Not applicable.
: The authors declare no competing interests.
