Lin, Junjie
Yin, Hehe
Xie, Zihan
Liu, Meihui
Kong, Lulu
Yao, Ruixuan
Chen, Guang
Li, Yuyao
Shen, Jiaojiao
Wang, Qingling
Han, Kexing
Xu, Honghai
Gao, Yufeng
Funding for this research was provided by:
National Natural Science Foundation of China (No. 82370608)
Natural Science Foundation of Anhui Province (No.2208085MH204)
Natural Science Foundation of Education Department of Anhui Province (No. 2022AH040160)
Anhui Provincial Special Fund for Clinical Medical Research Transformation (No.202304295107020040)
Article History
Received: 16 August 2025
Accepted: 3 November 2025
First Online: 13 November 2025
Declarations
:
: This study has been approved by the ethics review board, and all related ethical documents have been uploaded. Clinical registration Number: 2522424, Registration Date: October 31, 2022, full name of the ethics committee: Clinical Medical Research Ethics Committee of the First Affiliated Hospital of Anhui Medical University. Informed consent was obtained from all participants (or from a parent/guardian for minors). This study was conducted in strict alignment with the ethical principles and guidelines of the Declaration of Helsinki. Clinical Medical Research Ethics Committee of the First Affiliated Hospital of Anhui Medical University granted approval for this research (Ethical Number: 2522424).
: Not applicable.
: The study obtained written informed consent from all patients for their participation. Consent for publication: All authors have reviewed the manuscript and consented to its publication.
: The authors declare no competing interests.