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Authors
Song, Xiaoyan https://orcid.org/0009-0007-1022-4015
Li, Huihui https://orcid.org/0000-0001-7467-4823
Zhu, Yan https://orcid.org/0009-0003-0145-9366
Wei, Guohao https://orcid.org/0000-0002-1677-8250
Li, Xiaoqing https://orcid.org/0009-0006-7424-3680
Wei, Hongxuan https://orcid.org/0009-0005-2829-1676
Zhao, Huihui https://orcid.org/0000-0002-1768-3835
Zhu, Chuandong https://orcid.org/0000-0002-7040-812X
Chen, Fangfang https://orcid.org/0009-0008-1576-9126
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Funding
Funding for this research was provided by:
the Basic Research Project of Jinling Hospital (2023JCYJYB105)
the New Technology of Clinical Diagnosis and Treatment Project of Jinling Hospital (2023LCZLXB044, 22LCZLXJS58)
Medical Science and Technology development project of Nanjing (YKK22130)
Talent lift Fund projects of Nanjing Second Hospital (RCMS23006)
Nanjing Medical Science and Technology Development Project (ZKX23037)
Key Project of Talent Support Plan of Nanjing Second Hospital (RCZD202302)
National Health Commission Special Scientific Research Program on Post-Marketing Clinical Studies of Innovative Drugs (WKZX2024CX101211)
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Article History
Received: 13 May 2025
Accepted: 4 November 2025
First Online: 27 November 2025
Declarations
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: The authors are accountable for all aspects of the work, ensuring that any issues related to the accuracy or integrity of the study have been thoroughly investigated and resolved. The study involving human participants was conducted by the ethical standards of the Ethics Committee of Nanjing Second Hospital (Approval No.2024-LS-ky-012) and the Ethics Board of Jinling Hospital (Approval No.2020DZGZRZX-096), and written informed consent was obtained from all participants. All animal experiments were conducted in accordance with the ARRIVE guidelines and were approved by the Institutional Ethics Board of Jinling Hospital (Approval No. DZGZRDW240010). The study also conformed to the principles outlined in the Basel Declaration (accessible at: ) and complied with the China Laboratory Animal Laws (2017).
: Not applicable.
: The authors declare no competing interests.
