Nagayama, Gota https://orcid.org/0009-0001-6173-9824
Koseki, Hirokazu https://orcid.org/0000-0002-2939-7182
Ikemura, Ayako https://orcid.org/0000-0002-4304-9678
Otani, Katharina https://orcid.org/0000-0002-2322-3405
Karagiozov, Kostadin https://orcid.org/0000-0001-6105-0480
Kan, Issei https://orcid.org/0000-0003-4829-4784
Yuki, Ichiro https://orcid.org/0000-0002-7673-9085
Murayama, Yuichi https://orcid.org/0000-0003-3490-385X
Funding for this research was provided by:
Siemens Healthcare (C00221973)
Article History
Received: 7 July 2025
Revised: 7 November 2025
Accepted: 23 December 2025
First Online: 8 January 2026
Declarations
:
: The protocol of animal experiments was reviewed and approved by the Institutional Animal Care and Use Committee of The Jikei University School of Medicine (No. 2018-036) and conformed to the Guidelines for the Proper Conduct of Animal Experiments of the Science Council of Japan (2006). The work was reported per ARRIVE guidelines.
: This work was supported by a grant from Siemens Healthcare (ID C00221973). K.O. is a full-time employee of Siemens Healthcare K.K. All other authors have no competing interests to declare that are relevant to the content of this article.