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Authors
Mai, Ziling
Du, Huijun
Chen, Yuhan
Lu, Yaner
Liu, Bingchen
Sun, Deqiang
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Funding
Funding for this research was provided by:
Key Research and Development Program of Zhejiang Province (No.2025C02144)
National Key Research and Development Program of China (Project 2023YFA1800700 and 2022YFA1105200)
National Natural Science Foundation of China (NSFC, Project 81773012)
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Article History
Received: 25 November 2025
Accepted: 19 March 2026
First Online: 10 April 2026
Declarations
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: Cardiac valve tissue collection was approved by the Ethics Committee of the Second Affiliated Hospital, School of Medicine, Zhejiang University (No. 2024–0099) and written informed consent was obtained from all donors.
: Not applicable.
: The public datasets analyzed in this study are available in the GEO repository ( ).
: There are no conflicts of interest to be disclosed by all authors.
: The authors declare no competing interests.
