Yin, Peng
Li, Shihua
Li, Xiao-Jiang
Yang, Weili
Article History
Received: 7 January 2022
Accepted: 23 February 2022
First Online: 25 March 2022
Declarations
: This work was supported by The National Natural Science Foundation of China (81830032, 32070534, 31872779, 82071421); Key Field Research and Development Program of Guangdong province (2018B030337001), Department of Science and Technology of Guangdong Province (2021ZT09Y007; 2020B121201006), Guangzhou Key Research Program on Brain Science (202007030008), The National Key Research and Development Program of China Stem Cell and Translational Research (2017YFA0105102).
: The authors declare that they have no competing interests. Informed consent was obtained from all individual participants included in the study. Authors are responsible for correctness of the statements provided in the manuscript. All authors give their consent for the publication of this study.
: WY and PY wrote the manuscript. X-J L and SL edited the manuscript. All discussed and approved the overall structure of the review.
: AAV, adeno-associated viruses; AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; CMV, cytomegalovirus; CRISPR, clustered regularly interspaced short palindromic repeats; FTLD, fronto-temporal lobar degeneration; FUS, fused in sarcoma; HD, Huntington’s disease; HTT, huntingtin; NDs, neurodegenerative diseases; PD, Parkinson’s diseases; polyQ, polyglutamine; PRKN, parkin RBR E3 ubiquitin protein ligase ; SCNT, somatic cell nuclear transfer; sgRNA, single guide RNA; SNs, substantia nigras; SNCA, α-synuclein; SOD1, superoxide dismutase 1; SQSTM1, Sequestosome-1; SVZ, subventricular zone; TDP-43, TAR DNA-binding protein 43.