Zhang, Ping
Lu, Yongke
Li, Yanli
Wang, Kesheng https://orcid.org/0000-0001-7118-3877
An, Huimei
Tan, Yunlong
Funding for this research was provided by:
Natural Science Foundation of Beijing Municipality (7151005)
National Major Science and Technology Projects of China (81771452)
Article History
Received: 25 September 2022
Accepted: 1 June 2023
First Online: 6 July 2023
Declarations
:
: The authors declare no conflict of interests. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
: Ethical approval for the methylation study was approved by the Ethics Review Board of Beijing HuiLongGuan Hospital and informed consent was obtained from the patients and caregivers. All methods in this study were performed in accordance with the relevant guidelines and regulations. All the individuals were adults (aged 19–61) with Han Chinese ethnicity and living in Beijing. All subjects gave signed, informed consent to participation and were given written instructions to fast overnight before blood sampling.