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Induction of TRIM22 during Clonorchis sinensis infection triggers intracellular ROS accumulation by suppressing the mTOR-mediated Nrf2 signaling pathway

Crossref DOI link: https://doi.org/10.1007/s13258-025-01692-1

Published Online: 2025-10-21

Published Print: 2026-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jeong, Ji Hoon

Yi, Junyeong

Pak, Jhang Ho https://orcid.org/0000-0001-5104-5995
Funding

Funding for this research was provided by:

National Research Foundation of Korea (RS-2020-NR052182)
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Version of Record valid from 2025-10-21
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Article History

Received: 17 August 2025

Accepted: 23 September 2025

First Online: 21 October 2025

Declarations

:

: The authors declare no conflicts of interest concerning this study.

: The overall procedure and details of the animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of Inha University (approval no. INHA161208-460). 5–6-week-old male FVB/NJ mice were purchased from Central Lab Animal Inc. (Seoul, Korea). The mice were housed and cared for according to the National Animal Care policies (Accredited Unit, Korea FDA; unit number 36) in the Animal Facility of Inha University.

: Not applicable.

: Not applicable.

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