Pusalkar, Sandeepraj
Chowdhury, Swapan K.
Czerniak, Richard
Zhu, Xiaochun
Li, Yuexian
Balani, Suresh K.
Ramsden, Diane http://orcid.org/0000-0003-2994-0728
Funding for this research was provided by:
Takeda Pharmaceuticals U.S.A.
Article History
Accepted: 12 December 2021
First Online: 14 February 2022
Declarations
:
: This study was sponsored by Takeda Development Center Americas, Ltd.
: SP, SKC, RC, XZ, SKB, YL, and DR are/were employees of Takeda Development Center Americas, Inc., when this work was conducted, and received stock or stock options.
: All nonclinical studies conformed with the “Guideline for Non-clinical Pharmacokinetic Studies (Notification of the Pharmaceutical and Medical Safety Bureau, Ministry of Health and Welfare No. 496 as of June 26, 1998)” and the Data Integrity Standards for Product Application, Article 43 of the Enforcement Regulations of the Act on Securing Quality, Efficacy and Safety of Pharmaceuticals, Medical Devices, Regenerative and Cellular Therapy Products, Gene Therapy Products and Cosmetics (Ordinance of the Ministry of Health and Welfare No. 1 as of February 1, 1961) and were approved by the Institutions Animal Care and Use Committee.
: All volunteers provided written informed consent.
: Not applicable.
: All data and analysis generated during these studies are included in this article (and its supplementary information) or are available upon request to the corresponding author. All figures were prepared using GraphPad Prism v.8.0 (San Diego, CA).
: There was no code used in the analysis contained within this article.
: Participated in research design: SP, SKC, RC, XZ, SKB, YL. Conducted experiments: SKB, SP, XZ. Performed data analysis: DR, SKB, SKC, SP, XZ. Wrote or contributed to the writing of the manuscript: SP, SKC, XZ, SKB, DR.