Simoens, Caroline http://orcid.org/0000-0001-8446-052X
Philippaert, Koenraad http://orcid.org/0000-0002-5861-2275
Wuyts, Caroline http://orcid.org/0000-0002-9526-1590
Goscinny, Séverine http://orcid.org/0000-0002-2248-9930
Van Hoeck, Els http://orcid.org/0000-0002-1172-2338
Van Loco, Joris http://orcid.org/0000-0001-8439-3371
Billen, Jaak http://orcid.org/0000-0003-4852-4340
de Hoon, Jan http://orcid.org/0000-0002-5215-9836
Ampe, Els http://orcid.org/0000-0002-4675-8824
Vangoitsenhoven, Roman http://orcid.org/0000-0003-3523-669X
Mertens, Ann http://orcid.org/0000-0002-1649-4311
Vennekens, Rudi http://orcid.org/0000-0002-2564-5150
Van der Schueren, Bart http://orcid.org/0000-0003-4754-784X
Clinical trials referenced in this document:
Documents that mention this clinical trial
Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial
https://doi.org/10.1007/s13318-022-00792-7
Funding for this research was provided by:
KU Leuven (C14/17/091)
Fonds Wetenschappelijk Onderzoek (G0C2420N, GOE0217N)
Article History
Accepted: 31 July 2022
First Online: 3 September 2022
Declarations
:
: The study was funded by a KU Leuven Grant (TRPLe: TRP Research Platform Leuven - C14/17/091) and FWO Vlaanderen (G0C2420N and GOE0217N).
: There is no conflict of interest for any of the authors.
: The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.
: Not applicable.
: The study was approved by the institutional review board (Ethics Committee Research UZ/KU Leuven, Leuven, Belgium) and the national competent authority (Federal Agency for Medicines and Health Products (FAMPH), Belgium). The study was performed in accordance with the ethical standards of the 1964 Declaration of Helsinki and its later amendments.
: Informed consent was obtained from all individual participants prior to the initiation of any study-related procedure.
: Not applicable.
: CS, KP, RV and BVdS contributed substantially to the conceptualization of the study. CS, RVG, AM and BVdS recruited subjects, conducted the experiments and collected data. JdH coordinated the clinical team involved in practical assistance for the trial and the manufacturing of the drug. EA manufactured the drug. CS, SG, EVH and JVL analyzed the pharmacokinetic samples. CS, CW and JB analyzed the pharmacodynamic samples. CS and BVdS did the formal analysis. RV provided funding. BVdS supervised the project. CS drafted the manuscript, and RV and BVdS reviewed and edited the manuscript. All authors contributed to the interpretation of the data and critically revised the manuscript.
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