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Article History

Accepted: 25 May 2023

First Online: 27 June 2023

Declarations

:

: This work was supported by JSPS KAKENHI (grant number 21K06684).

: The authors declare no conflicts of interest.

: All authors contributed to the conception and design of the study. YI and YT performed material preparation, data collection, and analysis. The first draft of the manuscript was written by YI, and all authors commented on previous versions of the manuscript. All the authors have read and approved the final version of the manuscript.

: The experimental protocols were reviewed and approved by the Hokkaido University Animal Care Committee, in accordance with the “Guide for the Care and Use of Laboratory Animals” (study protocol number 21-0101). This study protocol was approved on November 5th, 2021.

: Not applicable.

: Not applicable.

: Not applicable.

: The data supporting the findings of this study are available from the corresponding author upon reasonable request.