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Article History

Accepted: 17 January 2024

First Online: 21 February 2024

Declarations

:

: Study concept and design: GZ, LW, and XH. Data acquisition: SZ, and SH. Data analysis and interpretation: SZ, SH, HP, and MT. GZ was primarily responsible for drafting the manuscript and all authors reviewed, edited, and approved the manuscript before submission.

: This work was partially supported by the Scientific Projects of Guangdong Province (2020A050515008); the Technology Innovation Project of Foshan (2017IT100153); and Guangzhou Magpie Pharmaceuticals Co., Ltd.

: The authors have indicated that they have no conflicts of interest regarding the content of this article.

: The clinical study met all local legal and regulatory requirements. The studies were conducted under contract with Guangzhou Magpie Pharmaceutical Co., Ltd., by the following research organizations, with approval from their ethical review committees: Haikou People's Hospital (approval number: 2019-(ethical review)-002, approval date: April 18, 2019). All procedures in these studies were performed in accordance with the 1964 Helsinki Declaration (and its amendments).

: The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.

: Not applicable.

: Informed consent was obtained from all individual participants prior to the initiation of any study-related procedure.

: Not applicable.