Document is current

Article History

Accepted: 22 January 2025

First Online: 1 February 2025

Declarations

:

: All patients in this study have signed informed consent forms and agreed that their data can be published.

: Tao-tao Liu designed the research. Lu-lu Niu, Yong-jun Liu, Yun Wu, Tian-min Huang, Ting-qing Wu, Yang Xiao, Xin Chen, Yi-lin Luo, collected and reviewed the data for this study. Lu-lu Niu establishing the PPK model and the simulation of the dosing regimens. Lu-lu Niu wrote the manuscript. All authors contributed to the interpretation of the results, the reviewing of the manuscript, and the decision to submit this manuscript to be published. All authors read and approved the final manuscript. All authors agreed to publish this work

: The data and code that support the findings of this study are available from the corresponding author upon reasonable request.

: The Ethics Committee of the First Affiliated Hospital of Guangxi Medical University approved the protocol (NO.2023-K130-01). This study complied with the Declaration of Helsinki and national and institutional standards. And all recruited patients, and their guardians signed the informed consent form before participating in the study.

: All patients and their guardians had signed informed consent before the study began.

: The authors declared no conflicts of interest concerning the research, authorship, and publication of this article.

: No funding was received for this work.