Osborne, Kenyon W. https://orcid.org/0009-0002-4586-8973
MacFater, Wiremu S. https://orcid.org/0000-0002-9323-7036
Anderson, Brian J. https://orcid.org/0000-0002-2826-3019
Svirskis, Darren https://orcid.org/0000-0001-9435-1773
Hill, Andrew G. https://orcid.org/0000-0001-8672-6379
Hannam, Jacqueline A. https://orcid.org/0000-0003-2974-7397
Funding for this research was provided by:
Health Research Council of New Zealand (18-013)
Univeristy of Auckland Faculty Research Development Fund
University of Auckland
Article History
Accepted: 15 April 2025
First Online: 8 May 2025
Declarations
:
: Wiremu MacFater was supported by a Health Research Council of New Zealand Career Development Award 18-013. The lidocaine RCT project was supported by The University of Auckland Faculty Research Development Fund.
: None.
: The deidentified dataset used in modeling for this work are available from the corresponding author upon reasonable request.
: New Zealand Northern Health and Disability Ethics committee provided ethics approval for the original lidocaine dataset used in this analysis (reference 17/NTB/93). Clinical trial registration was done in accordance with CONSORT statement ().
: Informed consent was obtained from all individual participants included in the study.
: Not applicable.
: The NM-TRAN control stream is available in the supplementary materials.
: JAH and KO created the datafiles. KO, JAH and BJA undertook the analysis. JAH and KO wrote the first draft of the paper. AGH, DS and WMF designed and conducted the original RCT. All authors contributed to critically reviewing the manuscript and gave their final approval for submission.