Document is current

Article History

Accepted: 19 February 2024

First Online: 1 March 2024

Declarations

:

: All institutional and national guidelines were followed. All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (Ethic Committee for the Investigation related with Human Beings (CEISH) of the UPV/EHU) and with the Helsinki Declaration of 1975, as revised in 2000 (5). Informed consent was obtained from all patients for being included in the study. Buffy coats from healthy donors were obtained at the Basque Biobank, which were isolated from the blood of healthy donors at the Basque Transfusion Centre; and heparin blood tubes were obtained from healthy donors at the University of the Basque Country (UPV/EHU). The transfer of samples has been designed in accordance with the requirements of Law 14/2007, of 3 July, on Biomedical Research and Royal Decree 1716/2011, of 18 November, which establishes the basic requirements for the authorisation and operation of biobanks for biomedical research purposes and the treatment of biological samples of human origin and regulates the operation and organisation of the National Register of Biobanks for biomedical research (CEIm CES-BIOEF 2023-06). The research protocol was approved by the Ethic Committee for the Investigation related with Human Beings (CEISH) of the UPV/EHU (M10_2022_131MR1). Volunteers gave written informed consent to use their blood samples as research material. Likewise, the handling of these cells was approved by the Research Ethics Committee with Biological Agents and Genetically Modified Organisms (CEIAB) of the UPV / EHU (M30_2022_132MR1).

: Not applicable.

: The authors declare no competing interests.

: All authors declare that they have no conflicts of interest to disclose.