,
McGuire, Jennifer L.
Gill, Alexander J.
Douglas, Steven D.
Kolson, Dennis L.
Funding for this research was provided by:
National Institute of Neurological Disorders and Stroke (K12 NS049453)
National Institute of Mental Health (F30 MH102120, 1P30 MH097488)
National Institute of Mental Health (P01 MS105303)
National Institute of Mental Health (R01 MH104134)
National Institute of Mental Health (R01 MH095671)
Article History
Received: 7 December 2015
Revised: 13 May 2016
Accepted: 26 May 2016
First Online: 6 June 2016
Compliance with ethical standards
: Original data collection for the CHARTER cohort was approved by the Human Subjects Protection Committees of each participating institution. All subjects provided written consent to participate in the CHARTER study. Data were originally obtained through comprehensive neuromedical, neurocognitive, psychiatric, and functional evaluations, and collection of blood, urine, and CSF samples (Heaton et al. ). The de-identified data and biological samples for the present substudy were obtained with permission of the CHARTER steering committee. Because the dataset and samples were de-identified and because our substudy did not involve patient contact, The Children’s Hospital of Philadelphia institutional review board determined (June 22, 2015) that this study did not qualify as human subjects research.
: The authors declare that they have no conflict of interest.