Gumbs, Stephanie B. H.
Stam, Arjen J.
Mudrikova, Tania
Schipper, Pauline J.
Hoepelman, Andy I. M.
van Ham, Petra M.
Borst, Anne L.
Hofstra, LMarije
Gharu, Lavina
van Wyk, Stephanie
Wilkinson, Eduan
de Witte, Lot D.
Wensing, Annemarie M. J. http://orcid.org/0000-0003-3790-8891
Nijhuis, Monique
Funding for this research was provided by:
Aidsfonds (P-13204, P-37203)
Article History
Received: 25 June 2023
Revised: 30 March 2024
Accepted: 3 April 2024
First Online: 7 May 2024
Declarations
:
: Fresh postmortem adult human brain tissue was provided by the Netherlands Brain Bank (NBB). All subjects gave their informed consent for inclusion before they participated in the study. The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Ethics Committee of VU Medical Center (VUMC, Amsterdam, The Netherlands). Paired CSF and plasma samples were obtained as part of the AIDS Therapy Evaluation in the Netherlands (ATHENA) cohort which includes patients by an opt-out principle.
: Informed consent was obtained from all subjects involved in the study.