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Authors
Li, Rong
Deng, Yinan
Liang, Jinliang
Hu, Zhongying
Li, Xuejiao
Liu, Huanyi
Wang, Guoying
Fu, Binsheng
Zhang, Tong
Zhang, Qi
Yang, Yang
Chen, Guihua
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Funding
Funding for this research was provided by:
National Key R&D Plan (2017YFA0104304)
National 13th Five-Year Science and Technology Plan Major Projects of China (2017ZX10203205)
the National Natural Science Foundation of China (81802897, 81702393, 81770648, 81670601, 81972286)
Guangdong Basic and Applied Basic Research Foundation (2015A030312013, 2016A030313195, 2018A030313259, 2017A030311034)
Science and Technology Program of Guangdong Province (2017B020209004,20169013,2017B030314027)
Science and Technology Program of Guangzhou city (2014Y2-00200,201604020001, 201508020262, 201400000001-3)
Sun Yat-sen University Young Teacher Training Project (19ykpy18)
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Article History
Accepted: 17 September 2020
First Online: 9 October 2020
Compliance with ethical standards
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: The authors declare that there is no conflict of interest.
: A total of 136 patients who were histopathologically and clinically diagnosed as HCC at the third affiliated hospital, Sun Yat-Sen University (Guangzhou, Guangdong, China) were recruited for this study. All procedures with human subjects in this study were conducted in accordance with the Institutional Research Ethics Committee. Informed written consent was obtained from all participants. Correlations between circ-102,166 expression and clinicopathological parameters and patient survival were analyzed using 77 HCC specimens with detailed clinical follow-up data. The expression profile of circ-102,166 was determined in the other 59 HCC specimens for which paired non-tumorous tissues were available. All experimental procedures involving animals were conducted in accordance with the Chinese legislation regarding experimental animals and were approved by the Animal Ethical and Welfare Committee (AEWC) of Guangzhou Forevergen Medical Laboratory Animal Center (No. GFAC-AEWC-118).
