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Article History

Received: 23 December 2021

Accepted: 8 April 2022

First Online: 2 May 2022

Declarations

:

: This study and the journal’s Rapid Service Fee was supported by Maruho Co., Ltd.

: All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published.

: All authors contributed to the study conception and design. All authors read and approved the final manuscript.

: We thank Diane Williams, PhD, from Edanz () for providing medical writing support. This assistance was funded by Maruho Co., Ltd.

: Makoto Kawashima has received consulting and speaker fees from Maruho Co., Ltd. Yoshiki Miyachi has received a consulting fee from Maruho Co., Ltd. The NPO Health Institute Research of Skin (Chiyoda-ku, Tokyo) planned and implemented the study.

: This study was reviewed and approved by the institutional review board of the NPO Health Institute Research of Skin (committee number: 19000025), and it allowed all institutions to participate in. This study was performed in accordance with the ethical principles of the Declaration of Helsinki and the ethical guidelines for medical research on humans. The study was registered in the University Hospital Medical Information Network (UMIN) Clinical Trials Registry. Written informed consent was obtained from all participants.

: The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.