Document is current

Article History

Received: 30 September 2024

Accepted: 22 October 2024

First Online: 12 November 2024

Declarations

:

: Melinda Gooderham has been an investigator, speaker, and/or advisor for: AbbVie, Acelyrin, Alumis, Amgen, Akros, Arcutis, Aristea, AnaptysBio, Apogee Therapeutics, Bausch Health, Bristol Myers Squibb, Boehringer Ingelheim, Cara Therapeutics, Dermira, Dermavant, Eli Lilly, Galderma, GSK, Incyte, Inmagene, JAMP Pharma, Janssen, LEO Pharma, L’Oreal, MedImmune, Meiji, MoonLake, Nektar, Nimbus, Novartis, Pfizer, Regeneron, Sanofi Genzyme, Sun Pharma, Tarsus, Takeda, UCB, Union, Ventyx, and Vyne. Emma Guttman-Yassky is an employee of Mount Sinai; this institution has received research grants from: LEO Pharma, Pfizer, Amgen, GSK, Incyte, Sanofi, Bristol Myers Squibb, ASLAN, Regeneron, AnaptysBio, Concert, Janssen, Q32 Bio, AbbVie, Eli Lilly, Arcutis, and Inmagene. Emma Guttman-Yassky has been a consultant for: AbbVie, Arcutis, Almirall, Amgen, AnaptysBio, Apogee Therapeutics, Apollo Therapeutics Limited, Artax Biopharma Inc., Astria, Bristol Myers Squibb, Boehringer Ingelheim, Calliditas Therapeutics, Cara Therapeutics, Celldex, Centrexion Therapeutics Corporation, Connect Biopharma, Coty, DBV Technologies, Eli Lilly, Enveda Biosciences, Escient Pharmaceuticals, Inc., Fairmount Funds Management LLC, FL2022-001, Inc., Galderma, Gate Bioscience, Google Ventures (GV), GSK Immunology, Incyte, Inmagene, Janssen Biotech, Jasper Therapeutics, Kymera Therapeutics, Kyowa Kirin, Leo Pharma, Matchpoint Therapeutics, Merck, Nektar Therapeutics, Novartis Pharmaceuticals, NUMAB Therapeutics AG, Nuvig, OrbiMed Advisors LLC, Otsuka, Pfizer, Pharmaxis Ltd, Pioneering Medicine VII, Inc., Proteologix US Inc., RAPT, RayThera, Inc., Regeneron Pharmaceuticals, RibonTherapeutics, Inc., Sagiment Biosciences, Sanofi, SATO, Schrödinger, Inc., Sitryx, Sun Pharma Advanced Research Company (SPARC), Takeda, Teva Branded Pharmaceutical Products R&D, Inc., TRex, UCB, and Ventyx Biosciences. Ken Igawa has received a lecture fee from: Sanofi, AbbVie, Lilly, Leo Pharma, Maruho, and Otsuka. Kenji Kabashima has received consulting fees, honoraria, grant support, and/or lecturing fees from: Amgen, Kyowa Kirin, Japan Tobacco, LEO Pharma, Maruho, Mitsubishi Tanabe, Ono Pharmaceutical, Procter & Gamble, Sanofi, Taiho, and Torii Pharmaceutical. Ehsanollah Esfandiari, Angela J Rylands and Angela Williams are employees of Kyowa Kirin International. Ehsanollah Esfandiari has stock options in Kyowa Kirin. Annabel Nixon and Jennifer E. Dent work for Chilli Consultancy, which received payment from Kyowa Kirin International for this work. Eric Simpson received personal fees from AbbVie, Amgen, Arcutis, Areteia Therapeutics, Bristol Myers Squibb, CorEvitas, Corvus, Dermira, Eli Lilly, Evelo Biosciences, FIDE, Forte Bio RX, Galderma, GlaxoSmithKline, Gilead Sciences, Impetus Healthcare, Incyte, Innovaderm Research, Janssen, Johnson & Johnson, Kyowa Kirin Pharmaceutical Development, LEO Pharma, Merck, NUMAB Therapeutics AG, Pfizer, Physicians World LLC, PRImE, Recludix Pharma, Regeneron, Roivant, Sanofi Genzyme, Sitryx Therapeutics, Trevi Therapeutics, and Valeant. Eric Simpson received research grants from or served as a principal investigator for: AbbVie, Acrotech, Amgen, Arcutis, ASLAN, Castle, CorEvitas, Dermavant, Dermira, Incyte, Lilly, Kymab, Kyowa Kirin, National Jewish Health, LEO Pharma, Pfizer, Regeneron, Sanofi, Target, and VeriSkin.

: The trial was conducted in accordance with the Declaration of Helsinki, the International Conference on Harmonization consolidated Good Clinical Practice guideline, and any applicable national and local laws and regulations. The protocol and all subsequent amendments were reviewed and approved by institutional review boards or independent ethics committees at each site. All subjects provided written informed consent.