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Article History

Received: 22 January 2025

Accepted: 7 March 2025

First Online: 21 March 2025

Declarations

:

: Jonathan I. Silverberg has received grants as a consultant and/or advisory board member for AbbVie, Alamar, Aldena, Amgen, AObiome, Arcutis, Arena, Asana, Aslan, BioMX, Biosion, Bodewell, Boehringer-Ingelheim, Cara, Castle Biosciences, Celgene, Connect Biopharma, Dermavant, Dermira, Dermtech, Eli Lilly, Galderma, GlaxoSmithKline, Incyte, Kiniksa, Leo Pharma, Menlo, Novartis, Optum, Pfizer, RAPT, Regeneron, Sanofi-Genzyme, Shaperon, Union; speaker for AbbVie, Eli Lilly, Leo Pharma, Pfizer, Regeneron, and Sanofi-Genzyme; institution received grants from Galderma, Incyte, and Pfizer. Danielle N. Rodriguez, Carla Dias-Barbosa, and Dina Filipenko are employees of Evidera, which was paid by Galderma for work relating to this study. Liliana Ulianov, Christophe Piketty, and Jorge Puelles are employees of Galderma, which funded this study.

: The clinical trials that provided data for this study were conducted in accordance with the Helsinki Declaration of 1964 and its later amendments, good clinical practice guidelines, and International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use guidelines. Both trials were initiated after approval from applicable regulatory authorities and the independent ethics committee or institutional review board at each participating site. All patients or their legal guardians provided written informed consent/assent prior to enrollment.