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Authors
Passeron, Thierry
Kerob, Delphine
Le Dantec, Guénaëlle
Demessant-Flavigny, Anne-Laure
do Nascimento, Alessandro R.
Moura, Renato
Salah, Samir
Feiges, Mariana
Fernandez, Erika
Alexis, Andrew
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Clinical Trials BETA
Clinical trials referenced in this document:
nct06787846 at ClinicalTrials.govDocuments that mention this clinical trial
Efficacy and Tolerability of a New Facial 2-Mercaptonicotinoyl Glycine-Containing Depigmenting Serum Versus Hydroquinone 4% over 3-Month Treatment of Facial Melasma
https://doi.org/10.1007/s13555-025-01473-4
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Article History
Received: 6 May 2025
Accepted: 12 June 2025
First Online: 30 June 2025
Declarations
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: Thierry Passeron has received honoraria from ACM, Beiersdorf, Galderma, L’Oréal, Hyphens, ISIS Pharma, ISDIN, NAOS, Pierre Fabre, SUN Pharma, SVR, and Symrise. Delphine Kerob, Guénaëlle Le Dantec, Anne-Laure Demessant-Flavigny, and Samir Salah are employees of La Roche-Posay Laboratoire Dermatologique. Alessandro R. do Nascimento and Renato Moura have no conflict of interest to declare. Mariana Feiges and Erika Fernandez are employees of L’Oreal. Andrew Alexis has received honoraria from Leo, Galderma, Pfizer, Sanofi-Regeneron, Dermavant, Beiersdorf, Ortho, L’Oreal, BMS, Bausch health, UCB, Vyne, Arcutis, Janssen, Allergan, Almirall, Abbvie, Sol–Gel, Amgen, VisualDx, Eli Lilly, Swiss American, Cutera, Cara, EPI, and Incyte.
: The protocol of this study was approved by an independent ethics committee from the Pró-Cardíaco Hospital, Rio De Janeiro, Brazil. The investigation was conducted in accordance with the principles of Resolution 466/2012 of the Conselho Nacional de Saúde do Brazil, ethical principles stipulated in the Declaration of Helsinki of 1964 (and its subsequent amendments), and Good Clinical Practice defined by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use. The patients provided consent for the publication of patient images.
