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Article History

Received: 12 August 2025

Accepted: 29 August 2025

First Online: 11 September 2025

Declarations

:

: Svenja Royeck was advisor, speaker or investigator for Incyte Inc., Eli Lilly, LEO Pharma and Sanofi/Regeneron outside the submitted work. Christian Mess, Meike Shedden Mora, Tobias B. Huber, Felix Witte, Konstantin Agelopoulos, Henning Wiegmann and Johannes B. Oehm have nothing to disclose. Angelika Weigel reports research funding (no personal honoraria) from the Werner Otto Foundation. She has received remunerations for a lecture at the Lindauer Psychotherapietage and she has been treasurer of the EAPM (unpaid) until 2023. Volker Huck has received research funding from LEO Pharma GmbH in terms of an investigator-initiated trial outside the submitted work. Bernd Löwe reports research funding (no personal honoraria) from the German Research Foundation, the German Federal Ministry of Education and Research, the German Innovation Committee at the Joint Federal Committee, the European Commission’s Horizon 2020 Framework Programme, the European Joint Programme for Rare Diseases (EJP), the Ministry of Science, Research and Equality of the Free and Hanseatic City of Hamburg, Germany and the Foundation Psychosomatics of Spinal Diseases, Stuttgart, Germany. He received remunerations for several scientific book articles from various book publishers, from the Norddeutscher Rundfunk (NDR) for interviews in medical knowledge programmes on public television, and as a committee member from Aarhus University, Denmark. He received travel expenses from the European Association of Psychosomatic Medicine (EAPM), and accommodation and meals from the Societatea de Medicina Biopsyhosociala, Romania, for a presentation at the EAPM Academy at the Conferința Națională de Psihosomatică, Cluj-Napoca, Romania, October 2023. He received a travel grant for a lecture on the occasion of the presentation of the Alison Creed Award at the EAPM Conference in Lausanne, 12–15 June 2024. He received remuneration and travel expenses for lecture at the Lindauer Psychotherapiewochen, April 2024. He is President of the German College of Psychosomatic Medicine (DKPM) (unpaid) since March 2024 and was a member of the Board of the European Association of Psychosomatic Medicine (EAPM) (unpaid) until 2022. He is member of the EIFFEL Study Oversight Committee (unpaid). Anne Toussaint reports research funding (no personal honoraria) from the German Research Foundation. She has received remunerations for a printed textbook from Ernst Reinhardt Publishing. The other authors have no conflict of interest to declare. Christoph Schramm was consultant for Pliant Therapeutics, Chemomab, Agomab, Amgen and Moonlake and received honoraria for lectures from Falk Foundation. Claudia Zeidler is an investigator for Novartis, Janssen, Pfizer, UCB, Lilly, Abbvie, Boehringer Ingelheim, Sanofi, Regeneron, Leo, Galderma and has received speaker honoraria/travel fees from Dermasence, Beiersdorf, Leo, Sanofi, Novartis, Unna Akademie, Almirall and AbbVie outside the submitted work. Matthias Augustin has served as a consultant or paid speaker or has received research grants or honoraria for consulting and scientific presentations or has received travel reimbursements or participated in clinical trials for companies that manufacture drugs for the treatment of pruritus/prurigo, including AbbVie, Almirall, Eli Lilly, Galderma, Novartis, Pfizer, Sanofi and Trevi. Stefan W. Schneider was speaker and/or consultant funding from Almirall S. A., GSK R&D Ltd., Incyte Corporation, LEO Pharma GmbH, Lilly Deutschland GmbH, Novartis Pharma GmbH, Sanofi-Aventis Deutschland GmbH, Pfizer Pharma GmbH. Sonja Ständer was speaker and/or consultant and/or Investigator and/or has received research funding from Amgen Inc., Almirall S. A., Celldex Therapeutics Inc., Clexio Biosciences Ltd., Focus-Insight Healthtech Group Co. Ltd., Galderma Laboratorium GmbH, Galderma R & D, LLC., Galderma SA, Klirna Biotech Inc., GSK R&D Ltd., Incyte Corporation, LEO Pharma GmbH, Lilly Deutschland GmbH, Novartis Pharma GmbH, P. G. Unna Academy, Sanofi-Aventis Deutschland GmbH, Sanofi-Aventis R& D, Sanofi Genzyme Corporation, TouchIME, Vifor Pharma Deutschland GmbH. Sonja Ständer is an Editorial Board member of Dermatology and Therapy . Sonja Ständer was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions.

: Reviewed and approved by the Ethics Committee of the State Medical Association of Westfalen-Lippe, Münster, Germany; approval # 2007-413-f-S. All participants provided written informed consent prior to their inclusion in the research.