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Authors
Xu, Jianfeng
Lei, Deng
Xu, Peng
Wang, Yuqi
Li, Zhupeng
Wu, Jiacheng
Feng, Weizhong
Zhou, Junqing
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Funding
Funding for this research was provided by:
Zhejiang Province Medical and Health Science and Technology Plan Project (2024KY1706)
Shaoxing Health Science and Technology Plan Project (2022KY013)
Shaoxing People's Hospital Cardiovascular Surgery Research Team Project (2021TD20)
Zhejiang Public Welfare Technology Application Research Project (LTGD23H010002)
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Article History
Received: 9 September 2025
Accepted: 13 December 2025
First Online: 24 December 2025
Declarations
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: The authors have no competing interests to declare that are relevant to the content of this article.
: The animal experiments in this study were conducted following the ARRIVE guidelines and the "Guiding Principles in the Care and Use of Animals" (China) and approved by the Ethics Committee of Shaoxing People’s Hospital (Approval number: 2024Z014). The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. The EC clinical samples were collected from patients with informed consent and ethical guidelines approved by the Academic Ethics Committee of Shaoxing People’s Hospital (Approval number: IEC-K-AF-070–1.2).
: Informed consent was obtained from all individual participants included in the study.
