Miyoshi, Yuka https://orcid.org/0000-0003-3141-6650
Nakayama, Akiyoshi https://orcid.org/0000-0002-6654-0726
Nakashima, Hiroshi https://orcid.org/0000-0001-9517-2080
Hashimoto, Itsumi https://orcid.org/0009-0006-1241-8713
Kawamura, Yusuke https://orcid.org/0000-0001-5021-1613
Shimizu, Seiko https://orcid.org/0009-0000-4749-9011
Toyoda, Yu https://orcid.org/0000-0002-7411-0531
Mizuno, Tomoko https://orcid.org/0009-0009-4518-5487
Tanabe, Risa https://orcid.org/0000-0003-3006-4761
Hamada, Yoshinobu https://orcid.org/0000-0001-5846-0702
Nagayoshi, Mako https://orcid.org/0000-0002-1196-146X
Kubo, Yoko https://orcid.org/0009-0007-8390-0299
Okada, Rieko https://orcid.org/0000-0002-6206-2501
Matsunaga, Takashi https://orcid.org/0009-0007-8075-2008
Yoshioka, Noriyuki
Iwasawa, Satoko https://orcid.org/0000-0001-8194-1432
Ueno, Miki https://orcid.org/0009-0004-5424-9060
Hayano, Kimiko https://orcid.org/0009-0003-7166-7582
Nakaoka, Hirofumi https://orcid.org/0000-0002-8454-1159
Yamamoto, Ken https://orcid.org/0000-0002-1531-9685
Wakai, Kenji
Shinomiya, Nariyoshi https://orcid.org/0000-0003-1497-487X
Matsuo, Hirotaka https://orcid.org/0000-0003-4302-8719
Funding for this research was provided by:
Japan Society for the Promotion of Science (24K22217)
Japan Society for the Promotion of Science (24K02695)
Japan Society for the Promotion of Science (20H00566)
Japan Society for the Promotion of Science (20K10522)
Japan Society for the Promotion of Science (16H06277)
Japan Society for the Promotion of Science (22H04923)
Japan Society for the Promotion of Science (221S0001)
Ministry of Defense- Japan
Suzuken Memorial Foundation
Gout and Uric Acid Foundation
National Defense Medical College
Article History
Received: 20 February 2026
Accepted: 9 April 2026
First Online: 18 June 2026
Declarations
:
: The authors declare that there is no conflict of interest.
: This study was approved by the Ethics Committee of the National Defense Medical College (Approval No. 4920).
: Written informed consent was obtained from all participants.