Bigaud, Marc http://orcid.org/0000-0002-1168-5311
Ramseier, Pamela
Tisserand, Sarah
Lang, Meike
Urban, Beatrice
Beerli, Christian
Karlsson, Göril
Funding for this research was provided by:
Novartis
Article History
Received: 10 February 2023
Accepted: 19 April 2023
First Online: 17 May 2023
Funding
: Novartis Pharma AG, Basel, Switzerland, funded the study and medical writing support for the preparation of this manuscript also funded the journal’s Rapid Service Fee.
: We thank Paul Coyle (Novartis Ireland) for providing medical writing support, which encompassed formatting of the manuscript content, referencing, tables and figures as per the journal guidelines, and incorporating the authors’ revisions and finalizing the draft for submission, all under the direction of the authors.
: Marc Bigaud, Pamela Ramseier, Sarah Tisserand, Meike Lang, Beatrice Urban, Christian Beerli and Goril Karlsson met the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval to the version to be published. All authors except Goril Karlsson were involved in generating the study data and were involved in the drafting and review of the manuscript; Goril Karlsson contributed to the study concept and design, and to the interpretation of the results and provided critical review of the manuscript. All authors are responsible for intellectual content and data accuracy.
: Preliminary parts of this work were previously presented at the American Academy of Neurology Congress, Philadelphia, Pennsylvania, USA, May 2019 [CitationRef removed], and at the ECTRIMS Congress, Stockholm, Sweden, September 2019 [CitationRef removed].
: Marc Bigaud, Pamela Ramseier, Sarah Tisserand, Meike Lang, Beatrice Urban, Christian Beerli and Goril Karlsson are employees of Novartis, except for Christian Beerli who has since retired, and all author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
: In accordance with the Declaration of Helsinki, the welfare of the animals used in these studies was respected. All in vivo studies were performed in accordance with protocols approved by the Cantonal Veterinary Office of Basel and according to regulations defined by the European Community Council Directive for animal protection.
: The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.