Gupta, Digant https://orcid.org/0000-0002-1963-8886
Kaur, Amandeep https://orcid.org/0009-0009-0412-0118
Verma, Vikas https://orcid.org/0009-0004-6495-1929
Van Oorschot, Désirée A. M. https://orcid.org/0000-0002-0382-0333
Penders, Yolanda https://orcid.org/0000-0002-7606-7987
Guzman-Holst, Adriana https://orcid.org/0000-0002-6753-2541
Funding for this research was provided by:
GlaxoSmithKline
Article History
Received: 14 August 2025
Accepted: 30 October 2025
First Online: 23 December 2025
Declarations
:
: Digant Gupta, Amandeep Kaur, and Vikas Verma are employees of Bridge Medical, which was contracted by GSK for this study; Désirée A. M. Van Oorschot, Yolanda Penders, and Adriana Guzman-Holst are employees of and hold financial equities in GSK.
: This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.
: This SLR and its meta-analyses were prospectively registered with PROSPERO, the international prospective register of systematic reviews ( ; #CRD42024587336).